DraftKings and FanDuel will stop running paid contests in New York amid an ongoing fight to operate in the key market. New York Attorney General Eric Schneiderman has sought to shut down the companies’ operations since last year, when he issued a cease-and-desist order, arguing their contests rely on chance and are illegal under state law. DraftKings and FanDuel have stressed their contests require skill, and they were previously allowed to operate while they appealed the injunction. “As I’ve said from the start, my job is to enforce the law, and starting today, DraftKings and FanDuel will abide by it.…
Author: Deep
After recently introducing the new Superb, Skoda India is planning to launch the updated Rapid in India by August this year. The revised Rapid will get the long overdue exterior and the interior modifications that make it look sleeker. The updated Rapid will flaunt Skoda’s redesigned front moustache grille and follow the design language as seen on the new Octavia and Superb. The headlamps will be toned down in terms of its current curved shape, and this time will be sharp and aggressive. From the recent spyshots, not many changes can be seen on the side and the rear section.…
Toyota Innova Crysta is confirmed for an India launch in the first week of May. The MPV, which is all new from the grounds up, was unveiled at the 2016 Auto Expo. The new Innova Crysta gets improved styling, a new engine, and upgrades in terms of features. Under the hood, the new Innova Crysta comes with a 2.4-litre diesel engine that puts out close to 150bhp of power. The older Innova came with a 2.5-litre diesel engine with 100bhp. Toyota will offer the new Innova Crysta with a five-speed manual and a six-speed automatic transmission. Toyota will also introduce…
KPI Therapeutics, a clinical stage biotechnology company presented promising pre-clinical animal results using drugs from its platform of novel Kv1.3 inhibitors as topical therapy for uveitis, an autoimmune eye disease. The results presented at the 8th Ocular Diseases Drug Discovery Conference showed topical administration of these agents reduced disease severity and the infiltration of damaging inflammatory cells in an animal model of anterior uveitis. Administration of the drug to the surface of the eye was well-tolerated and resulted in significant penetration into the anterior chamber of the eye. Using novel peptides from the same family as its lead autoimmune drug…
A Massachusetts General Hospital (MGH) investigator has found that increased expression of the angiogenic factor VEGF-A promotes three common aging-related eye conditions – both versions of age-related macular degeneration (AMD) and also cataracts – in an animal model. While VEGF-A was known to be associated with neovascular or ‘wet’ AMD, whether it was a direct cause of the condition was unknown. Its role in ‘dry’ AMD was even less certain, and its contribution to cataract formation was totally unexpected. “Our finding that shared pathologic mechanisms contribute to these three conditions identifies potential molecular targets for treating or even preventing their…
Nintendo shares spiked over 8 percent Tuesday after the company’s first mobile app, Miitomo, racked up a million users in three days. Miitomo was released last Thursday and over the weekend, the official Twitter account for the app announced the grand total. Miitomo, which is only currently available in Japan, was also number one on Apple’s App store in the country, according to analytics firm App Annie. Tuesday is the first trading day back in Japan after a public holiday and Nintendo investors reacted positively to the news. Mobile is seen as a key part of Nintendo’s strategy for the…
JetSmarter, widely considered the Uber for jets, is going the extra mile to help users get closer to their favorite celebrities. The private transportation start-up, which is part of a disruptive clutch of companies trying to make private jets more affordable, now offers a function to notify members when certain celebrities will be on a flight — allowing them to hitch a ride. Thus far, JetSmarter’s clientele include celebrities who fly private, yet aren’t megastars like Tom Cruise or Sean “Jay-Z” Carter, who each own their own private planes. “Passengers and celebs will get a lot of networking value,” Sergey…
Damien Meyer | AFP | Getty Images Microsoft set out to learn about “conversational understanding” by creating a bot designed to have automated discussions with Twitterusers, mimicking the language they use. What could go wrong? If you guessed, “It will probably become really racist,” you’ve clearly spent time on the Internet. Less than 24 hours after the bot, @TayandYou, went online Wednesday, Microsoft halted posting from the account and deleted several of its most obscene statements. More from the New York Times: Starboard Value seeks to oust Yahoo’s board Keeping up with Android security patches Google fined by French privacy…
It’s not a hair-brained idea: A new research report appearing in the April 2014 issue of The FASEB Journal explains why people with a rare balding condition called “atrichia with papular lesions” lose their hair, and it identifies a strategy for reversing this hair loss. Specifically the report shows for the first time that the “human hairless gene” imparts an essential role in hair biology by regulating a subset of other hair genes. This newly discovered molecular function likely explains why mutations in the hairless gene contribute to the pathogenesis of atrichia with papular lesions. In addition, this gene also…
Super-sonic signal: A signal from Transit-Amplifying Cells (TACs) activates stem cells in the hair follicle, researchers have found. Both types of cells appear in green (top), with TACs clustered lower down. The researchers identified the signal as Sonic Hedgehog. In experiments, such as this one (bottom), they disabled the signal, interfering with hair growth and regeneration. Credit: Image courtesy of Rockefeller University Stem cells switch off and on, sometimes dividing to produce progeny cells and sometimes resting. But scientists don’t fully understand what causes the cells to toggle between active and quiet states. New research in Elaine Fuchs’ Laboratory of…